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Melanoma

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Aeromedical Implications

Effect of aviation on condition

  • Hypoxia - lowers seizure threshold and thus risk from cerebral secondaries
  • Fatigue and jet lag will tend to aggravate any adverse effects of radiotherapy and chemotherapeutic agents

Effect of condition on aviation

  • Overt incapacitation
    • seizure risk is major hazard
  • Subtle incapacitation
    • pain
    • depression and affective disorders
    • medication side-effects (heart, lungs, liver, kidneys, immune competence)
  • Distraction due to treatment & symptoms eg pain and nausea

Approach to medical certification

Based on the condition

  • Incapacitation risk
  • Risk of metastasis
  • Absence of symptoms / complications including psychological

Based on Treatment

  • Adequate clearance

Demonstrated Stability

  • May include interim surveillance

Risk assessment protocol - Information required

New cases

  • Confirmed diagnosis
  • Clinical status
    • presenting symptoms/signs eg lymphadenopathy
  • Investigations conducted
    • Results of staging investigations/histology
    • Follow-up investigations
  • Management
    • treatment
    • monitoring
  • Prognosis
  • Risk of possible future recurrence
    • What are the likely clinical presentations of recurrence?
    • Could this be accompanied by incapacitating symptoms?
    • Could a recurrence be detected before symptoms occur by increasing the frequency of radiological, haematological or other surveillance?
  • Follow-up plan

Renewal

  • Current clinical status
    • symptoms/signs
    • skin check
    • lymph node examination
  • Investigations conducted
    • Follow-up investigations eg skin excisions, imaging/ PET scans, lymph node biopsies
  • Management
    • treatment
    • monitoring
  • Prognosis
  • Risk of possible future recurrence
    • What are the likely clinical presentations of recurrence?
    • Could this be accompanied by incapacitating symptoms?
    • Could a recurrence be detected before symptoms occur by increasing the frequency of radiological, haematological or other surveillance?
  • Follow-up plan.

Indicative outcomes

Prognostic data from AJCC may be helpful

Favourable

  • Low risk melanoma - confirmed histology and fully excised

Unfavourable

  • Metastatic melanoma
  • Melanoma with an unacceptable risk of metastasis
  • Melanoma  requiring radiotherapy or chemotherapy

Pilot & Controller Information

  • It is very important to provide the laboratory report about any skin lumps or moles removed. This provides the base information to enable an assessment
  • CASA may require annual dermatologist or GP reports for 5 years following treatment for low risk melanoma
  • Applicants with unacceptable metastasis risk may not meet the required standard for medical certification
  • Multi-crew restriction may be applied in some cases depending on risk of metastasis

Disclaimer

The Clinical Practice Guideline is provided by way of guidance only and subject to the Clinical practice guidelines disclaimer